Understanding Life, Development, and Disease

Welcome to the department of Developmental and Cell Biology at UC Irvine.

Leading the way to Discovery

Department of Developmental and Cell Biology (DCB)

The Department of Developmental and Cell Biology investigates the fundamental processes that shape living systems, from the regulation of individual cells to the development and function of complex organisms. Faculty research spanning a broad range of areas and experimental systems, explores questions with implications for human health, including the origins of cancer, mechanisms of tissue repair, and the causes of developmental disorders. Through research and teaching, the department provides students with opportunities to engage with basic biological discoveries and their applications to disease, regenerative medicine, and the development of new therapies.

Fluorescence Microscope image of Bovine Pulmonary Artery Endothelial Cells BPAE stained for mitochondria, phalloidin, and nuclei undergoing mitosis
Aimee Edinger

Faculty

A world class faculty dedicated to advancing knowledge about how cells function, communicate, grow, and develop into complex organisms.

Student in Lab

Undergraduates

Exciting opportunities exist for Dunlop School majors interested in pursuing a degree in Developmental and Cell Biology or Genetics.

group of students

Graduates

Entering through 3 interdisciplinary doctorate programs, Developmental and Cell Biology graduates will be prepared examine compelling biological questions.

Research at DCB

Our research programs investigate how cell growth, differentiation, and morphogenesis are controlled to build the tissues and organs. To address fundamental questions in biology, we deploy cutting-edge approaches, including genomics, proteomics, advanced microscopy, and AI-guided data analysis, across diverse organisms and experimental systems. Grounded in an integrative approach and a collaborative culture, our community fosters discovery, and trains students to become the next generation of scientific leaders.

News

Dunlop School Celebrates Faculty Excellence in Teaching and Mentorship

Helping students understand science, build confidence and envision their futures takes dedicated educators. The Charlie Dunlop School of Biological Sciences is celebrating two such faculty members, Katherine Thompson-Peer and Andrea Nicholas, who were recognized at UC Irvine’s 34th annual Celebration of Teaching on Sept. 17, 2026. Thompson-Peer, an assistant professor of developmental and cell biology,…

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Small fish, big possibilities: UCI BioEYES brings science to Santa Ana classrooms

A child’s opportunity to explore science should not depend on access to a university laboratory. Yet bringing hands-on research into middle school classrooms requires equipment, expertise and sustained support. As science shapes everyday decisions about health and the environment, giving young people opportunities to investigate, question and understand evidence matters. Since 2022, UCI BioEYES has…

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UC Irvine Study Reveals How Damaged Tissue Can Limit Nerve Cell Repair

Dual-imaging of class IV ddaC sensory neurons (green) and epidermis (magenta) in live, third instar Drosophila larvae. Credit: Imaged by Mia A Brantley Irvine, Calif., September 30, 2026 — When a traumatic injury damages the nervous system, understanding what prevents nerve cells from repairing themselves is critical to improving recovery. Yet many laboratory studies examine…

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Deep Learning Designs DNA Switches That Turn Genes On In Mouse Embryos

A transgenic mouse embryo in which AI-designed regulatory DNA sequences drive gene expression in the forebrain (red) and in the midbrain (green). Image credit: Ethan Hollingsworth Irvine, Calif., August 25, 2026 — One of biology’s enduring challenges is explaining how cells carrying the same genetic instructions develop into such different organs like the heart, brain…

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Making Science Matter: Cameron Geller Wins UCI Grad Slam

Second-place finisher Tessa Chou, first-place finisher Cameron Geller and third-place finisher Mehdi Zafari pose with their awards following the 2026 UC Irvine Grad Slam competition. PhD candidate Cameron Geller of the Department of Developmental & Cell Biology has been named the 2026 UC Irvine Grad Slam Champion, earning top honors in a campuswide competition that…

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Dr. Ken Cho has an AAAS Fellow award and a Pew Scholar in Biomedical Sciences.

Dr. Michael Parson’s lab created a method to ablate cells at will to study regeneration. This method has been used in over 2,300 publications to date.

Dr. Kavita Arora was a recipient of the Searle Scholar Award.

Dr. Scott Atwood discovered how basal cell carcinoma gains resistance to targeted therapy.

Faculty Spotlight

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Xiaoyu Shi, Ph.D.,

Professor

Making the Invisible Visible: Mapping Cells at the Nanoscale in Health and Disease – We develop super-resolution microscopy and spatial multiomics to reveal the organization of proteins, lipids, RNA, and DNA within cells and tissues. Combining expansion microscopy with spatial proteomics, we map changes in biomolecular identity, abundance, and distribution during aging, Alzheimer’s disease and cancer. Our goal is to uncover disease mechanisms and identify biomarkers that enable earlier diagnosis and guide precision treatments.

> Learn more about Dr. Shi’s research here.

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