Abstract: Conventionally, the size, shape, and biomechanics of cartilages are determined by their voluminous extracellular matrix. By contrast, we found that multiple murine cartilages consist of lipid-filled cells called lipochondrocytes. Despite resembling adipocytes, lipochondrocytes were molecularly...

Olivier Cinquin has published a new paper in Briefings in Bioinformatics on the pitfalls and possibilities of using large language models like ChatGPT to help with bioinformatic analysis.   Abstract: Large language models (LLMs) leverage factual knowledge from pretraining....

Congratulations to Dr. Pablo Lara-Gonzalez and Dr. Lee Bardwell! The Lara-Gonzalez lab, in collaboration with the Bardwell lab, recently published amanuscript titled “Cyclin B3 is a dominant fast-acting cyclin that drives rapid earlyembryonic divisions” in...

Laurence Seabrook and Melissa Campos, from Lauren Albrecht's lab, recently published a paper, "Methylarginine targeting chimeras for lysosomal degradation of intracellular proteins". Abstract: A paradigm shift in drug development is the discovery of small molecules that harness...