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Dr. Dhanya Cheerambathur

Group leader at the Wellcome Centre for Cell Biology, School of Biological Sciences, University of Edinburgh, UK.

“New Horizons for Chromosome Segregation Machinery in Wiring the Brain”

Abstract:

The brain is made up of billions of neurons that form trillions of intricate connections. The precise mechanisms governing the formation of these neural networks during brain development remains a mystery. In my talk, I will delve into a surprising discovery related to the post-mitotic activities of the chromosome segregation machinery in brain wiring. We have uncovered a previously unknown function of highly conserved kinetochore proteins, typically known for linking DNA to microtubules during mitosis, in patterning the dendrites and axons. Our research suggests that kinetochore proteins play a pivotal role in orchestrating the actin cytoskeleton within developing neurons, emerging as key regulators that shape the neural networks.

 

For more info about Dr. Cheeramathur's research:

https://www.research.ed.ac.uk/en/persons/dhanya-cheerambathur 


Seminar will be held in person only.

Details

Date:
May 9
Time:
11:00 am - 12:00 pm

Venue

4201 Natural Sciences II
4201 Natural Sciences II
Irvine, CA 92697 United States

Organizer

Mayra Rubio
Phone:
949-824-1969
Email:
mrubio3@uci.edu

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