DEPARTMENT OF DEVELOPMENTAL AND CELL BIOLOGY

 

Graduate Student Handbook (Fall 2003)

A guide for graduate students after their first year in the MBGB program

 

 

DEPARTMENTAL OFFICE AND ADMINISTRATION

                                                                                                                                                           

 

Rm/MH

Ext.

Email

Arthur D. Lander

Chair

Rm 5205

41721

adlander@uci.edu

Thomas F Schilling

Graduate Student Advisor

Rm. 5210

42479

tschilli@uci.edu

Nancy Johnson

Department Administrator

Rm. 5205

44706

 njohnson@uci.edu

Linda Pawloski

Contracts and Grants

Rm. 5218

43489

ldpawlos@uci.edu

Terri Buchanan

Payroll and Personnel

Rm. 5215

44707

buchanat@uci.edu

Eleanor Chan

Financial Analyst

Rm. 5216

49869

echan@uci.edu

Li-Yu Chen

Financial Analyst

Rm. 5216

44710

liyuc@uci.edu

Mayu McKenzie

Financial Analyst

Rm. 5205

45687

mmckenzi@uci.edu

Linda Fernandez

Graduate Student

Rm. 5207

46681

 lcfernan@uci.edu

 

Coordinator

 

 

 

Larrie Adanza

Assistant  to the Chair

Rm. 5205

45347

cadanza@uci.edu

 

For matters concerning enrollment, progress, deadlines etc. please contact Dr. Tom Schilling or Ms. Linda Fernandez.

 

The department office, Rm. 5205, has a Fax machine available for legitimate business use only.  For photocopying, you will be provided with a personal number by your faculty sponsor.  Copy machines are located on the 2nd, 4th, and 5th floors.  For copying services in the libraries, you will need a copy card.

 

The BioSci Computing Lab, located at MLH 200, is available to you.   

 

Parking/Escort services are available 24/7, 365 days a year on campus, University Apartments and University Center.  Call 824-SAFE (7233).

 

EMERGENCIES:

 

You have access to fire, rescue and police at the 911 emergency number.  The non-emergency number for campus police is 824-5223 (45223 from campus phones).

 

LABORATORY USE:

 

Your research advisor’s laboratory is under his/her direction.  You need to receive formal training and certification in the use and disposal of toxic and radioactive waste.

 


STIPENDS AND ENROLLMENT: 

 

You must enroll each quarter through TELE.  You are expected to enroll full time (minimum 12 units) each quarter.  This is YOUR responsibility each quarter.  A late fee of $25 is assessed if not paid by fee deadline, increasing to $50 if you have not enrolled by the second week of the quarter.

 

The consequences of late registration are:

a)     You must pay the late fee as described above.

b)     On non-student status, you will have federal deductions from your paycheck which will affects your eligibility for housing.

c)      You must use an add/drop card to enroll in the courses.

 

For US citizens who are non-residents of California, you should become a legal resident of the state by the beginning of the second year.  This will reduce the tuition fees considerably.  A change of residency must be recorded in the Registrar’s Office BEFORE the fee deadline. Normally the deadline is four weeks before the starts of the Fall quarter.  For the documentation required, call the Registrars office at extension 46124.

 

For foreign students, tuition is reduced to the California resident rate after advancement to candidacy.  This reduction in rate is a very important savings for the grant that is paying the stipend.  Advancement to candidacy should be achieved by the end of the third year or earlier.

 

Every student receives a stipend from the Department on the same schedule, unless they are on a training grant.  The schedule changes when you move from the Combined Program to a Department.  This results in one month gap with no pay (the Combined Program pays at the beginning of the month in advance; the Departments pay at the end of the month in the arrears).

 

Graduate students have health benefits and eligibility for student loans provided with full-time enrollment.

 

FINANCIAL AID:

 

Traineeships: Beyond stipends from Departmental sources, including Teaching Assistantships and research funds that support the student’s laboratory, several Traineeships on a variety of NIH or other Training Grants are available.  The directors of various Training Grants announce notice of openings to the faculty members and student sponsors who make nominations of students.

 

Campus Dissertation Fellowships:  These are designed for students in the last quarter of their degree work.  These fellowships are competitive and are announced once or twice each year by the Graduate Advisor.

 

Travel: The school, Training Grants, and the Graduate Division have modest funds for support of travel to meetings.  These funds are used for students to present their research. 

Dissertation Directors commonly have funds in their research grants to provide for travel to meetings or other institutions for experimental work.

 

Other fellowships: A number of UC and national fellowship programs provide support for graduate study.  Students may take initiative in obtaining these awards, and the Graduate Advisor will attempt to provide information about them as they become available.

 

ACADEMIC PROGRESS:

 

The Department’s academic requirements incorporate those of the Combined Program in Molecular Biology, Genetics and Biochemistry.  The program is your academic home during your first year.

 

Required Courses:

NOTE: All courses must be passed with a grade of B or better, or by an S (satisfactory).  Students receiving a C or lower must rpeat the course before they can advance. 

 

First Year:     Students must enroll in the following courses for a minimum of 12 units each  quarter.

Fall:                Mol. Bio. 204, Structure/Biosynthesis of Proteins

Winter:           Mol. Bio. 203, Structure/Biosynthesis of Nucleic Acid: and either Dev. Cell 231B, Cell Biology or Dev. Cell 231D, Molecular, Cellular and Developmental Neurobiology.

Spring:           Dev. Cell 210, Advanced Developmental Genetics, or Mol Bio. 206, Regulation of Gene Expression; or Mol. Bio./Bio. Chem., 207, Advanced Developmental Genetics.

 

In addition you will need to enroll in Dev & Cell 200 research, 203, Laboratory and 201, Seminar.

 

For additional Core-Electives and course descriptions, refer to the University Catalogue.    

 

Second Year:         

Each quarter you must enroll in a suitable number of units in the 200 and 203 series.  In addition it is also mandatory you enroll and attend the weekly Department Seminars Series, 290 and Journal Club, 206, Advanced Topics in Cell Biology.  As a Teaching Assistant this year you will also need to enroll in 399, University Teaching. 

 

Third Year and beyond:

Requirements are 12 units, which can be attained by the 200 and 203 series, 206, Journal Club and 290 Seminar Series.

 


OVERVIEW OF DEVELOPMENTAL AND CELL Ph.D. REQUIREMENTS

 

Year 2

Selection of your thesis advisor makes you a member of the graduate program in Developmental and Cell Biology. In addition to finishing the classes that are required in the MBGB program, and the TA assignments, you will also be expected to participate in least one-journal club per quarter and attend Departmental Seminars as a member of Developmental and Cell Biology. During this second year you should, in conjunction with your advisor, identify an interesting, tractable research problem, which will result in a thesis over the following 2-3 year period. You should focus on developing the knowledge and technical skills necessary to successfully complete the proposed project.

 

Year 3

 

Fall: Choosing an Advancement Committee:

You will select a 5-member advancement to candidacy committee before the end of fall quarter in the 3rd year. First presentation to the committee will occur at the end of fall quarter and requires the student to prepare a short 1-2 page outline regarding progress to date and proposed thesis direction. The committee should provide input and feedback that may influence the direction and focus of the advancement to candidacy exam in the spring quarter of the 3rd year.

 

Spring: Advancement timing:

Advancement will generally occur at the end of the 3rd (Spring) quarter of the 3rd year. By this time the student will have been in the lab just under 2 years and should have generated enough preliminary data to allow evaluation of the thesis project chosen and the likelihood of success.

 

Advancement format:

A written proposal in NIH format (approx 10 pages in total length) should be prepared by the candidate and distributed to the committee at least 1 week prior to advancement. The thesis advisor will prepare a written summary of the meeting and the committee and student should sign it. These two documents must be filed in the Department Office before the advancement documents are sent to Graduate Studies. If a terminal masters is recommended then the student will have 3 months in which to complete the research and to write a Masters Thesis.

 

Year 4 and beyond

 

Fall and Spring Tune-ups

Each student is required to do 2 tune-ups/year until receiving Ph.D.

 

Format of Tune-ups

A one page summary of the past 6 months progress will be prepared by the student and presented to each committee member at the tune-up meeting. The student's file containing the advancement proposal, 6 monthly summaries, and 6 monthly comments of the committee will be brought to the meeting. A written summary of the outcome of meeting and any comments by the committee will be recorded on a prepared form. This will be signed by the advisor, committee members and the student and will be retained by the Department Office.

 

Final Ph.D. time frame and research goal establishment

The 6-month tune-up at the end of the 4th year or beginning of the 5th year will be a comprehensive overview of current progress to date. At this meeting a series of experiments to be accomplished for the Ph.D. and a tentative end date will be discussed.

 

Evidence of quality of research by publication in peer reviewed journals

It is expected that a student receiving a Ph.D. will be able to identify a significant body of work that they have been primarily responsible for the formulation of the experiments, acquisition and interpretation of the data, and writing of the manuscripts. Students who entered the Dept. as 2nd year students in the fall of 1999 or earlier must have at least one first author or joint first author paper that is published or is submitted for publication in a peer reviewed journal before the thesis defense can be scheduled. Students who enter the Dept. as 2nd year students after the fall of 1999 must have at least one first author or joint first author paper that is accepted for publication in a peer reviewed journal before the thesis defense can be scheduled.

 

Teaching

Students will be required to fulfill their teaching obligations through the MBGB program during their second year of graduate school or as soon as possible. You will remain a second year and will not be able to advance until your TA ship is complete.

 

 

OUTLINE OF REQUIREMENTS

 

Year 2

            - Thesis advisor

            - Coursework for MBGB program

            - TA assignments

            - One journal club/quarter

            - Departmental seminars

 

Year 3

            - Pre-advancement (fall quarter)

                        5-person thesis committee

                        Submit 1-2 page outline summarizing progress and proposal

                        Meet with committee

            - Advancement (spring quarter)

                        Submit proposal in NIH format (approx 10 pages) at least a week in advance

                        meet with committee

 

Year 4 and beyond

            - Fall and spring tune-ups

                        Submit one-page summary of progress to each committee member

                        meet with committee

 

Preparing to defend your thesis

            - Special tune-up (spring of year 4 or fall of year 5)

            - Meet with committee to discuss overall progress and proposed defense date

-One first author paper is required to graduate

 

CHOOSING AN ADVANCEMENT COMMITTEE

 

In the fall of your third year you must choose a committee to oversee your advancement to candidacy. The committee is composed of a minimum of 5 faculty members. The chairman of the committee is your thesis advisor. The majority of members (at least 3/5 or 4/6 etc.) must be “internal” faculty members, appointed in Developmental and Cell Biology. In addition, at least one committee member must be "external", having a UC faculty appointment not in Dev and Cell Biology, but in some other Department.  This member can have an appointment in any other Department or School at UCI, including biologically-related disciplines.

 

***The proposed candidacy committee must be approved by your Principal Investigator and the Graduate Advisor at least one week prior to your meeting with them in the Fall quarter 2003.

 

PREADVANCEMENT

 

All graduate students in Developmental and Cell Biology are required to meet with their committee twice a year from the 3rd year on. One of these meetings is scheduled for late fall and the other for late spring.  Your first meeting will take place in the fall and is a “pre-advancement” requirement. It is your responsibility to schedule this meeting and to submit a 1-2 page outline of your progress and thesis proposal to each member of the committee.  The goal of this meeting is to provide input and feedback on your thesis proposal ideas from the faculty at an early date.

 

SCHEDULING COMMITTEE MEETINGS OR “TUNE UPS”

 

You and your committee agree to a date and time for the tune-up.

You contact the graduate coordinator to reserve a room.

 

Tune-up format:

This first meeting should be designed to acquaint the committee with your research area, both the major questions your work addresses and the preliminary studies you have done and hope to do in the next six months. A suggested outline for the presentation is 25-40 min. with some background information, data (gels, graphs etc. ) and summary. The level of formality at this meeting is up to the student and his or her committee, but generally it should be relatively informal with an emphasis on use of overheads and the chalk board.

 


Timing:

            Fall tune-up: Scheduled by 12/1/03; Completed by 12/15/03

 

ADVANCEMENT TO CANDIDACY EXAM

 

The following guideline was prepared to provide clarity on the purpose and format of the exam, and serve as a description and guideline for your preparation for your advancement.

 

Goal:

The purpose of the exam is to determine if the student is capable of Ph.D. quality research.  This encompasses two related aspects: 1) defining a tractable research problem; and 2) demonstrating requisite knowledge, skills and experimental sophistication to convince the committee that there is a high probability for the project to succeed.

 

Timing:

The Advancement Exam must be taken in the spring quarter of the 3rd year. 

 

***All students will be expected to have scheduled the exam by June 1st, 2004 and completed the exam before June 15th, 2004 

 

 

 

Written Proposal Format:

Prepare a written thesis proposal that follows conventional format for a federal grant application or high quality journal within your discipline.  The manuscript should be prepared with proper scientific nomenclature, as would be acceptable to a journal or granting agency.  The document should be double-spaced and is expected to be approximately 10-15 pages.   Please check with your advisor for details on the style of the document. 

 

In some form, the document will include:

1.      Introduction to the research project in which the problem and objectives are clearly stated and placed in context.  A bibliography should be included. 

 

2.      Preliminary results obtained by the student’s research efforts.  Appropriate discussion and methods should be included.  Figures and tables should be included with legends. 

 

3.      Proposed research for the thesis.  The research proposal should outline in the order of priority and time sequence the expected progress of research.  The proposal should address the feasibility of various experiments and point out caveats that might be encountered and how these could be circumvented. 

 

***The document should be distributed to the advancement committee at least one week prior to the oral presentation.

 

 

Oral Presentation format:

The oral portion of the exam will involve the presentation of background material, preliminary results and a summary of proposed experiments.  The presentation should be 30-40 minutes, although committee discussion will usually interrupt the flow.  During this time the committee will evaluate whether or not you have the ability to formulate questions on important biological questions.  You may be asked to discuss experimental design, required controls for an experiment, and possible artifacts or caveats. You will be expected to place the significance of the research project in a broad context. Although the exam analyzes different aspects of your ability than the more knowledge-oriented first year exam, you will be expected to demonstrate in-depth knowledge of the discipline in which you are working.  Thus, you should be prepared to elaborate on the background information within that discipline if requested by the committee.

 

***The exam should be scheduled for a three hour time period, although typically last about two hours. The graduate coordinator will help schedule the room etc.

 

Possible outcomes and consequences:

There are four possible consequences of the exam:

1.      you pass the exam and should expect to go into 1-3 more years of lab work to complete the Ph.D. thesis;

2.      you do not pass, which may have several consequences ranging from having to prepare a new advancement document OR providing additional experimental results OR additional tutorial or course work to remedy any deficiencies;

3.      you may be transferred to a Masters degree program; 4)  you may be terminated from the graduate program. 

 

Timetable for the 3rd year:

 

By 12/1/03                 Choose a committee

                                    Obtain approval for committee choices 1 week prior to meeting

                                    Submit 1-2 page outline of progress and thesis proposal ideas

 

By 12/15/03              Meet with committee (prepare a 30-40 minute presentation)

 

By 6/1/04                   Schedule advancement exam

                                    Submit 10-15 page thesis proposal 1 week prior to meeting

 

By 6/15/04                 Advancement exam (prepare a 30-40 minute presentation)

 

4th year students

All students who have passed their qualifying exam are required to meet with their committee every year, preferably twice a year (one of these meetings can be waved if the student and their advisor notify the graduate advisor in writing as to why they need not meet). One of these meetings is scheduled for late fall and the other for late spring. The ¾ schedule is given now so there will be no confusion as to the dates and what is required. A form which each of you will take to the tune-up is to be signed by your committee members and returned to the graduate office following the exam. This is to provide input and feedback for the students from the faculty.

 

Fall Tune-up:

Scheduled by  12/01/03

Completed by 12/15/03

 

Scheduling:

            You and your committee agree to a date and time for tune-up

            You contact the graduate coordinator and book a room.

 

Format:

            You will present your ongoing research, problems, interpretations of data etc.

 

Completion:

The tune-up will not be considered complete until a form signed by your advisor and committee members is returned to the graduate coordinator. This form will have two categories

1.      The above student is making satisfactory progress toward their Ph.D. See comments:

2.      The above student is not making satisfactory progress toward their PhD. See comments:

 

Should you fall into the second category you will meet with the graduate advisor and the thesis advisor to discuss the options.

 

End of 4th year tune-up

            Scheduled by 06/01/03

            Completed by 06/15/03

 

This tune-up will have two components, in addition to the normal discussion of progress during the past 6 months.

  1. Short summary of your research accomplishments during the past 4 years
  2. Series of experiments to be accomplished for the Ph.D. and a tentative end date will be discussed.

 

Suggested Format:

15 min.           Summary of research accomplishments including things such as: describe questions addressed highlight any papers prepared, submitted, published describe techniques mastered, developed

 

30 min.           Go over in more detail the progress over the past 6 months data interpretations

                        problems encountered

 

15 min.           Describe experiments to be finished for PhD and timetable.   Outline of  experiments, noting whether you will be a) cranking the handle on a well established protocol or b) still developing experimental protocols. Timetable for completion of particular projects including preparation and submission of manuscripts.  Timetable for completion of thesis and defense.

 

Remember that if you are thinking about defending your thesis anytime soon you must have at least one first author or joint first author paper that is accepted for publication in a peer-reviewed journal before the thesis defense can be scheduled.

 

5th –7 th years

Students who have passed their qualifying exam are required to meet with their committee every year, preferably twice a year (one of these meetings can be waved if the student and their advisor notify the graduate advisor in writing as to why they need not meet). One of these meetings is scheduled for late fall and the other for late spring. A form which each of you will take to the tune-up is to be signed by your committee members and returned to the graduate office following the exam. This is to provide input and feedback for the students from the faculty.

 

Scheduling:

             You and your committee agree to a date and time for tune-up

             You contact the graduate coordinator and reserve a room

 

Format:

            You present your ongoing research, problems, interpretations of data etc. Completion:

The tune-up will not be considered complete until a form signed by your advisor and committee members is returned to the graduate coordinator Coordinator. This form will have two categories

           

1.      The above student is making satisfactory progress toward their Ph.D. See comments:

2.      The above student is not making satisfactory progress toward their Ph.D. See comments:

Should you fall into the second category you will meet with the graduate advisor and the thesis advisor to discuss the options.

 

Timing:

            Fall tune-up:

                        Scheduled by 12/1/03

                        Completed by 12/15/03

            Spring tune-up:

                        Scheduled by 6/1/2004

                        Completed by 6/15/2004